Treatment Allocation under Uncertain Costs

03/20/2021
by   Hao Sun, et al.
0

We consider the problem of learning how to optimally allocate treatments whose cost is uncertain and can vary with pre-treatment covariates. This setting may arise in medicine if we need to prioritize access to a scarce resource that different patients would use for different amounts of time, or in marketing if we want to target discounts whose cost to the company depends on how much the discounts are used. Here, we derive the form of the optimal treatment allocation rule under budget constraints, and propose a practical random forest based method for learning a treatment rule using data from a randomized trial or, more broadly, unconfounded data. Our approach leverages a statistical connection between our problem and that of learning heterogeneous treatment effects under endogeneity using an instrumental variable. We find our method to exhibit promising empirical performance both in simulations and in a marketing application.

READ FULL TEXT

page 1

page 2

page 3

page 4

research
02/26/2018

Selecting optimal subgroups for treatment using many covariates

We consider the problem of selecting the optimal subgroup to treat when ...
research
10/04/2022

Estimating heterogeneous treatment effects versus building individualized treatment rules: Connection and disconnection

Estimating heterogeneous treatment effects is a well-studied topic in th...
research
02/14/2021

Optimal designs for the development of personalized treatment rules

In the present paper, personalized treatment means choosing the best tre...
research
11/16/2021

Practical Guidance on Modeling Choices for the Virtual Twins Method

Individuals can vary drastically in their response to the same treatment...
research
01/18/2022

Individualized treatment rules under stochastic treatment cost constraints

Estimation and evaluation of individualized treatment rules have been st...
research
04/23/2022

An Efficient Approach for Optimizing the Cost-effective Individualized Treatment Rule Using Conditional Random Forest

Evidence from observational studies has become increasingly important fo...
research
08/01/2020

Application of Bayesian Dynamic Linear Models to Random Allocation Clinical Trials

Random allocation models used in clinical trials aid researchers in dete...

Please sign up or login with your details

Forgot password? Click here to reset