research
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08/24/2023
Estimating hypothetical estimands with causal inference and missing data estimators in a diabetes trial
The recently published ICH E9 addendum on estimands in clinical trials p...
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01/27/2023
G-formula for causal inference via multiple imputation
G-formula is a popular approach for estimating treatment or exposure eff...
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02/07/2022
Estimands and their Estimators for Clinical Trials Impacted by the COVID-19 Pandemic: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions
The COVID-19 pandemic continues to affect the conduct of clinical trials...
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07/09/2021
Hypothetical estimands in clinical trials: a unification of causal inference and missing data methods
The ICH E9 addendum introduces the term intercurrent event to refer to e...
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11/23/2020